Alcohol is a depressant that can effect people in a huge variety of ways - some folk are pleasantly relaxed by the drug, others lose their inhibitions completely while for the less fortunate it can turn them into mumbling, dribbling bores or crazed psychotic nutters.
Alcohol slows reaction times, so some activities - like driving, cycling and operating machinery - can get decidedly dodgy. When you're off your box, your ability to make rational decisions goes flying out the window too and this can lead to sexual risk taking (if you're capable - it can also seriously affect performance in that department!) and the increased chance of catching HIV and other sexually transmitted diseases.
Taking a large dose of alcohol can cause memory loss, so you might not even remember what you said or why. Long-term use of alcohol is known to cause many physical illnesses including liver damage, stomach cancer and heart disease
Alcohol causes the body to lose heat to the environment - the blood vessels dilate, bringing them closer to the surface of the skin
Alcohol use has been linked to lots of social problems, including domestic violence and violent crime. The loss of inhibitions can lead to agressive behaviour. It might also lead to relationship problems - being drunk isn't much of an excuse if you say something to a friend you regret the next day.
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